BIRC3 polyclonal antibody
产品名称： BIRC3 polyclonal antibody
英文名称： BIRC3 polyclonal antibody
产品编号： PAB4708
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of BIRC3.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BIRC3.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Heterogeneous copy numbers of API2-MALT1 chimeric transcripts in mucosa-associated lymphoid tissue lymphoma.
Suguro-Katayama M, Suzuki R, Kasugai Y, Nakamura T, Suzuki H, Hosokawa Y, Shiku H, Nakamura S, Seto M.Leukemia. 2003 Dec;17(12):2508-12.
- 2.
- Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B.
Wang Q, Wang X, Evers BM.J Biol Chem. 2003 Dec 19;278(51):51091-9. Epub 2003 Oct 3.
- 3.
- cIAP-2 block apoptotic events in bladder cancer cells.
Jonsson G, Paulie S, Grandien A.Anticancer Res. 2003 Jul-Aug;23(4):3311-6.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of A-549 cell lysate (35 ug/lane) with BIRC3 polyclonal antibody (Cat # PAB4708).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with BIRC3 polyclonal antibody (Cat # PAB4708) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 330
- Protein Accession#:
- BIR3_HUMAN
- Gene Name:
- BIRC3
- Gene Alias:
- AIP1,API2,CIAP2,HAIP1,HIAP1,MALT2,MIHC,RNF49
- Gene Description:
- baculoviral IAP repeat-containing 3
- Omim ID:
- 601721
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq
- Other Designations:
- TNFR2-TRAF signaling complex protein,apoptosis inhibitor 2,baculoviral IAP repeat-containing protein 3,inhibitor of apoptosis protein 1,mammalian IAP homolog C