RUNX1 monoclonal antibody (M05), clone 4E7
产品名称： RUNX1 monoclonal antibody (M05), clone 4E7
英文名称： RUNX1 monoclonal antibody (M05), clone 4E7
产品编号： H00000861-M05
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant RUNX1.
- Immunogen:
- RUNX1 (NP_001001890.1, 210 a.a. ~ 310 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- RVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFP
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Isotype:
- IgG2b Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.85 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- RUNX1 monoclonal antibody (M05), clone 4E7 Western Blot analysis of RUNX1 expression in Hela NE ( Cat # L013V3 ).
- Protocol Download
- Western Blot (Cell lysate)
- RUNX1 monoclonal antibody (M05), clone 4E7. Western Blot analysis of RUNX1 expression in NIH/3T3 ( Cat # L018V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to RUNX1 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to RUNX1 on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged RUNX1 is approximately 1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 861
- GeneBank Accession#:
- NM_001001890
- Protein Accession#:
- NP_001001890.1
- Gene Name:
- RUNX1
- Gene Alias:
- AML1,AML1-EVI-1,AMLCR1,CBFA2,EVI-1,PEBP2aB
- Gene Description:
- runt-related transcription factor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- AML1-EVI-1 fusion protein,acute myeloid leukemia 1,aml1 oncogene,core-binding factor, runt domain, alpha subunit 2
- Related Disease
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Blast Crisis
- Cardiovascular Diseases
- Colitis, Ulcerative
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Disease Susceptibility
- Edema
- Genetic Predisposition to Disease
- Immune System Diseases
- Leukemia, chronic myeloid
- Leukemia, Myelocytic, Acute
- Leukemia, Myeloid, Acute