分子量：Calculated MW: 48kDa
Observed MW: 52kDa

细胞定位：Cell membrane, Multi-pass membrane protein

稀释方法：WB 1:500 - 1:1000
IHC 1:50 - 1:200

总结：This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.