COL1A1 monoclonal antibody (M01), clone 3G3
产品名称： COL1A1 monoclonal antibody (M01), clone 3G3
英文名称： COL1A1 monoclonal antibody (M01), clone 3G3
产品编号： H00001277-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant COL1A1.
- Immunogen:
- COL1A1 (NP_000079.1, 1021 a.a. ~ 1108 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- EGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIK
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Isotype:
- IgG3 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.42 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- COL1A1 monoclonal antibody (M01), clone 3G3. Western Blot analysis of COL1A1 expression in NIH/3T3(Cat # L018V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to COL1A1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged COL1A1 is 0.03 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 1277
- GeneBank Accession#:
- NM_000088
- Protein Accession#:
- NP_000079.1
- Gene Name:
- COL1A1
- Gene Alias:
- OI4
- Gene Description:
- collagen, type I, alpha 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish
- Other Designations:
- alpha 1 type I collagen,collagen alpha 1 chain type I,collagen of skin, tendon and bone, alpha-1 chain,pro-alpha-1 collagen type 1,type I collagen alpha 1 chain
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Aortic Aneurysm, Abdominal
- beta-Thalassemia
- Body Weight
- Bone Diseases
- Bone Diseases, Metabolic
- Bone Neoplasms
- Cardiovascular Diseases
- Chorioamnionitis
- Chronic Disease
- Clubfoot
- Colles' Fracture
- Connective Tissue Diseases
- Coronary Artery Disease
- Crohn Disease
- Crohn's disease
- Cystic Fibrosis
- Cystic fibrosis