分子量：Calculated MW: 242kDa/246kDa/267kDa
Observed MW: 256kDa

细胞定位：Cytoplasm, cell cortex, cytoskeleton

稀释方法：WB 1:500 - 1:2000
IHC 1:50 - 1:200

总结：This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described.