分子量：Calculated MW: 60kDa/80kDa
Observed MW: 85kDa

细胞定位：Endoplasmic reticulum, Golgi apparatus

稀释方法：WB 1:500 - 1:2000

总结：This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.