分子量：Calculated MW: 74kDa/109kDa/112kDa/113kDa
Observed MW: 113kDa

细胞定位：Cell membrane, Melanosome, Multi-pass membrane protein

稀释方法：WB 1:500 - 1:1000
IHC 1:50 - 1:200
IP 1:50 - 1:100

总结：The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.