产品概述：Purified recombinant protein of Human wingless-type MMTV integration site family, member 3 (WNT3), with C-terminal DDK tag, secretory expressed in CHO cells, 20ug

蛋白长度：A DNA sequence from GoldORF clone, [GH40920V], encoding the region Gly22-Lys355 of WNT3

表达系统：CHO

种属：Human

标签类型：C-DDK

分子量：37.4 kDa

通用名：WNT3

总结：The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region. [provided by RefSeq, Jul 2008]

形式：Liquid

浓度：>50 ug/mL as determined by Bradford protein assay

纯度：> 90% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：PBS, pH7.4, 10% glycerol

别名：INT4; TETAMS