别名：bHLHc12; MAD4; MST149; MSTP149

产品概述：Carrier-free (BSA/glycerol-free) MXD4 mouse monoclonal antibody, clone LBI1A2

总结：This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]