MET (Y1235D) (Human) Recombinant Protein
产品名称: MET (Y1235D) (Human) Recombinant Protein
英文名称: MET (Y1235D) (Human) Recombinant Protein
产品编号: P5729
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Human MET (NP_000236.2, 956 a.a. - 1391 a.a.) Y1235D mutant partial recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 76
- Form:
- Liquid
- Preparation Method:
- Baculovirus infected insect cell (Sf49) expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 62 % by SDS-PAGE/CBB staining.
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
Substrate : Srctide. ATP: 100 µM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 4233
- Protein Accession#:
- NP_000236.2
- Gene Name:
- MET
- Gene Alias:
- AUTS9,HGFR,RCCP2,c-Met
- Gene Description:
- met proto-oncogene (hepatocyte growth factor receptor)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- HGF receptor,OTTHUMP00000069168,SF receptor,met proto-oncogene,met proto-oncogene tyrosine kinase,oncogene MET,scatter factor receptor
- Interactome
- Related Disease
- Adenocarcinoma
- Autistic Disorder
- Carcinoma, Adenosquamous
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Cell Transformation, Neoplastic
- Child Development Disorders, Pervasive
- Chronic Disease
- Cognition Disorders
- Disease Progression
- Gastrointestinal Diseases
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Hyperparathyroidism, Secondary
- Lung Neoplasms
- Myopia
- Nasal Polyps
- Neoplasm Metastasis