分子量：Calculated MW: 40kDa/89kDa
Observed MW: 90KDa

细胞定位：Lipid-anchor, Membrane

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:200

总结：The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).