RPTOR polyclonal antibody
产品名称： RPTOR polyclonal antibody
英文名称： RPTOR polyclonal antibody
产品编号： PAB14657
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RPTOR.
- Immunogen:
- A synthetic peptide corresponding to amino acids 1050-1064 of human RPTOR.
- Sequence:
- DWEKGEKLDYFHNGN
- Host:
- Rabbit
- Reactivity:
- Bovine, Chicken, Chimpanzee, Dog, Human, Mouse, Rat, Zebra fish
- Specificity:
- The amino acid sequence used as immunogen is 100% homologous in human, mouse, rat, bovine, dog, chimp and chicken and 86% in zebrafish.
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.025% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Okazaki N, Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S, Saga Y, Nagase T, Ohara O, Koga H.DNA Res. 2003 Aug 31;10(4):167-80.
- 2.
- Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action.
Hara K, Maruki Y, Long X, Yoshino K, Oshiro N, Hidayat S, Tokunaga C, Avruch J, Yonezawa K.Cell. 2002 Jul 26;110(2):177-89.
- Application Image
- ELISA
- Entrez GeneID:
- 57521
- Protein Accession#:
- NP_065812
- Gene Name:
- RPTOR
- Gene Alias:
- KOG1,Mip1
- Gene Description:
- regulatory associated protein of MTOR, complex 1
- Omim ID:
- 607130
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats,regulatory associated protein of mTOR
- Gene Pathway