IDH3B polyclonal antibody
产品名称： IDH3B polyclonal antibody
英文名称： IDH3B polyclonal antibody
产品编号： PAB19676
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of IDH3B.
- Immunogen:
- A synthetic peptide corresponding to amino acids 33-46 near N-terminus of human IDH3B.
- Sequence:
- C-HAASRSQAEDVRVE
- Host:
- Goat
- Theoretical MW (kDa):
- 41.9
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is expected to recognize isoform a (NP_008830.2) and isoform b (NP_777280.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 3420
- Protein Accession#:
- NP_008830.2;NP_777280.1
- Gene Name:
- IDH3B
- Gene Alias:
- FLJ11043,H-IDHB,MGC903
- Gene Description:
- isocitrate dehydrogenase 3 (NAD+) beta
- Omim ID:
- 604526
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
- Other Designations:
- NAD+-specific ICDH,NAD+-specific isocitrate dehydrogenase b subunit,NAD+-specific isocitrate dehydrogenase beta,OTTHUMP00000030023,OTTHUMP00000030024,isocitrate dehydrogenase 3, beta subunit,isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, beta s
- Gene Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Citrate cycle (TCA cycle)
- Metabolic pathways