别名：AGS; AGS1; AHD; AWS; CD339; HJ1; JAGL1

产品概述：Carrier-free (BSA/glycerol-free) JAG1 mouse monoclonal antibody, clone LBI3A10

总结：The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]