别名：LGMD1; LGMD1A; MFM3; TTID; TTOD

产品概述：Carrier-free (BSA/glycerol-free) MYOT mouse monoclonal antibody,clone LBI5E11

总结：This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2008]