Anti-MICA Polyclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
Anti-MICA Polyclonal Antibody

Anti-MICA Polyclonal Antibody

商家询价

产品名称: Anti-MICA Polyclonal Antibody

英文名称: Anti-MICA Polyclonal Antibody

产品编号: K000346P

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: 2025-01-22T09:40:21

使用范围:

北京索莱宝科技有限公司
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Anti-MICA Polyclonal Antibody

品牌:solarbio | 货号:K000346P
商品货号:商品品牌:规格基本售价:选择规格
K000346P-50ulsolarbio50ul960.00元
K000346P-100ulsolarbio100ul1600.00元
英文名称Anti-MICA Polyclonal Antibody
别名MIC-A;PERB11.1
应用WB
稀释比例WB 1:500-2000.
交叉反应Human Mouse Rat
蛋白分子量43kDa
Gene ID100507436
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG
免疫原Recombinant protein of human MICA
性状液体
Public Immunogen RangeRecombinant protein of human MICA
Subcellular LocationsCell membrane Cytoplasm Single-pass type I membrane protein
Swiss ProtQ29983
克隆类型Polyclonal Antibody
背景资料This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.