Anti-NUP98 Polyclonal Antibody

品牌：solarbio | 货号：K001697P

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001697P-50ul	solarbio	50ul	960.00元
K001697P-100ul	solarbio	100ul	1600.00元

英文名称 Anti-NUP98 Polyclonal Antibody
别名 ADIR2;NUP196;NUP96
应用 WB
稀释比例 WB 1:1000-2000.
交叉反应 Human Mouse
蛋白分子量 198kDa
Gene ID 4928
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human NUP98
性状 液体
Public Immunogen Range Recombinant protein of human NUP98
Subcellular Locations Nucleoplasmic side Nucleus Nucleus membrane Peripheral membrane protein nuclear pore complex
Swiss Prot P52948
克隆类型 Polyclonal Antibody
背景资料 Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin.

英文名称	Anti-NUP98 Polyclonal Antibody
别名	ADIR2;NUP196;NUP96
应用	WB
稀释比例	WB 1:1000-2000.
交叉反应	Human Mouse
蛋白分子量	198kDa
Gene ID	4928
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human NUP98
性状	液体
Public Immunogen Range	Recombinant protein of human NUP98
Subcellular Locations	Nucleoplasmic side Nucleus Nucleus membrane Peripheral membrane protein nuclear pore complex
Swiss Prot	P52948
克隆类型	Polyclonal Antibody
背景资料	Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin.