分子量：Calculated MW: 84kDa/102kDa/103kDa
Observed MW: 105kDa

细胞定位：Nucleus

稀释方法：WB 1:500 - 1:2000

总结：This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.